One notable feature added in, that was previously introduced to the series in Grand Theft Auto: Chinatown Wars, is a scoring system with missions, which gauges how well the player did in accomplishing certain goals in a mission, ranging from minimising damage to themselves, achieving a fast time, to completing unique actions for that mission.
The scoring system also includes the ability to replay previously passed missions to improve a score on it, on condition that the player has completed the game's main story.
The storyline focuses on Luis' efforts to help Prince, who is the owner of the two largest nightclubs in Liberty City and a high-status socialite, overcome several issues, including drugs, debt, mafia families and attempts on both of their lives.
The story also ties up loose ends in regards to the diamond deal of Grand Theft Auto IV.
Multiplayer's modes, including free mode, deathmatch, team deathmatch, race and GTA Race modes, were updated, with a new "BASE jumping" (multiplayer competition) mode being introduced, as a variation of free mode.